Development of an NF1-OPG Pig Model

This project aims to accelerate translational research by characterizing pre-clinical models including the NF1-deficient and OPG-bearing Ossabaw pig and perform pilot studies designed to determine …

Development of Genetically Engineered Mouse Models for NF1-associated Optic Pathway Gliomas

To facilitate the translation into clinical practices, the Zhu lab will employ two clinically relevant assays to characterize these NF1-OPG models, the optomotor response (OMR) …